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Bethyl Laboratories
TKS4 Polyclonal Antibody
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TKS4 Antibody (A303-436A) in IP
Detection of human TKS4 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-TKS4 antibody (Product # A303-436A) used for IP at 6 µg/mg lysate. TKS4 was also immunoprecipitated by rabbit anti-TKS4 antibody A303-437A, which recognizes a downstream epitope. For blotting immunoprecipitated TKS4, A303-437A was used at 1 µg/mL,. Detection: Chemiluminescence with an exposure time of 10 seconds.
产品信息
A303-436A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 300 and 350 of Human Tyrosine Kinase Substrate with Four SH3 Domains.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adapter protein HOFI; adaptor protein HOFI; Factor for adipocyte differentiation 49; FLJ20831; SH3 and PX domain-containing protein 2B; Tyrosine kinase substrate with four SH3 domains
基因别名: FAD49; FTHS; HOFI; KIAA1295; SH3PXD2B; TKS4; TSK4
UniProt ID: (Human) A1X283
Entrez Gene ID: (Human) 285590
skeletal system development
eye development
superoxide metabolic process
heart development
extracellular matrix disassembly
cell differentiation
positive regulation of catalytic activity
positive regulation of fat cell differentiation
oxidation-reduction process
bone development
adipose tissue development
podosome assembly
protein localization to membrane
