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NeoBiotechnologies
TLE1 (Synovial Sarcoma Marker) Recombinant Rabbit Monoclonal Antibody (MSVA-856R)
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FIGURE: 1 / 1
TLE1 (Synovial Sarcoma Marker) Antibody (7088-RBM9-P1) in IHC (P)
Transducin-like enhancer protein 1 Rabbit Recombinant Monoclonal Antibody (MSVA-856R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
7088-RBM9-P1
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
MSVA-856R
Immunogen
Recombinant human TLE1 fragment (aa 175-338) (exact sequence is proprietary).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product cellular localization: Nucleus.
Positive control: Lung: Nuclear TTF1 staining should be strong in pneumocytes and in basal cells of the terminal bronchioles while a weaker, still moderate to strong staining should be seen in columnar epithelial cells of the terminal bronchioles (low expressor control).
Tissue specificity: Thyroid and lung.
Target Information
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1; RP11-203D19.1; TLE 1; Transducin-like enhancer protein 1
Gene Aliases: TLE1
Entrez Gene ID: (Human) 7088
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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