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Abnova
TLE3 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
H00007090-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TLE3 (AAH41831, 1 a.a. approximately 772 a.a) full-length human protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPPPPPLSCL RGLQAPHQPG QPGFKFTVAE SCDRIKDEFQ FLQAQYHSLK VEYDKLANEK TEMQRHYVMY YEMSYGLNIE MHKQTEIAKR LNTILAQIMP FLSQEHQQQV AQAVERAKQV TMTELNAIIG QQLQAQHLSH ATHGPPVQLP PHPSGLQPPG IPPVTGSSSG LLALGALGSQ AHLTVKDEKN HHELDHRERE SSANNSVSPS ESLRASEKHR GSADYSMEAK KRKAEEKDSL SRYDSDGDKS DDLVVDVSNE DPATPRVSPA HSPPENGLDK ARSLKKDAPT SPASVASSSS TPSSKTKDLG HNDKSSTPGL KSNTPTPRND APTPGTSTTP GLRSMPGKPP GMDPIGIMAS ALRTPISITS SYAAPFAMMS HHEMNGSLTS PGAYAGLHNI PPQMSAAAAA AAATYGRSPM VGFDPHPPMR ATGLPSSLAS IPGGKPAYSF HVSADGQMQP VPFPHDALAG PGIPRHARQI NTLSHGEVVC AVTISNPTRH VYTGGKGCVK IWDISQPGSK SPISQLDCLN RDNYIRSCKL LPDGRTLIVG GEASTLTIWD LASPTPRIKA ELTSSAPACY ALAISPDAKV CFSCCSDGNI AVWDLHNQTL VRQFQGHTDG ASCIDISHDG TKLWTGGLDN TVRSWDLREG RQLQQHDFTS QIFSLGYCPT GEWLAVGMES SNVEVLHHTK PDKYQLHLHE SCVLSLKFAY CGKWFVSTGK DNLLNAWRTP YGASIFQSKE SSSVLSCDIS ADDKYIVTGS GDKKATVYEV IY
Target Information
The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: enhancer of split groucho 3; enhancer of split groucho-like protein 3; ESG-1; ESG-2; ESG-3; ESG-4; Tle1; Tle2; tle4; transducin like enhancer of split 3; transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 3, homolog of Drosophila E(sp1); unnamed protein product
Gene Aliases: ESG; ESG3; GRG3; HsT18976
UniProt ID: (Human) Q04726
Entrez Gene ID: (Human) 7090
regulation of transcription, DNA-templated
signal transduction
organ morphogenesis
fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
white fat cell differentiation
negative regulation of canonical Wnt signaling pathway
negative regulation of cold-induced thermogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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