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Invitrogen
TLR10 Polyclonal Antibody
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产品信息
PA5-20054
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A peptide corresponding to 14 amino acids near the middle of human TLR10.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Despite its predicted molecular weight of ~90kDa, TLR10 is observed at ~75kDa in immunoblot assays. A suggested positive control is human lymph node tissue lysate.
PA5-20054 can be used with blocking peptide PEP-0173.
靶标信息
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Its exact function is not known. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CD290; MGC104967; MGC126398; MGC126399; Toll-like receptor 10
基因别名: CD290; TLR10; UNQ315/PRO358
UniProt ID: (Human) Q9BXR5
Entrez Gene ID: (Human) 81793
