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Invitrogen
TM4SF18 Monoclonal Antibody (211116)
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产品信息
MA5-23931
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
211116
抗原
NS0 mouse myeloma cell line transfected with human TM4SF18 Met1-Ile201
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody stains human TM4SF18-transfected cells but not parent cells.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Transmembrane 4 L Six Family Member 18 (TM4SF18) is a gene located on chromosome 11q12.3 that belongs to the transmembrane 4 L six superfamily, a group of proteins characterized by the presence of four transmembrane domains. TM4SF18 is expressed in various tissues and is involved in cellular processes such as cell adhesion, migration, and proliferation. As part of the tetraspanin family, TM4SF18 proteins play a role in organizing cellular membranes and facilitating interactions between cell surface receptors, impacting signaling pathways crucial for maintaining cellular functions and tissue homeostasis. Although TM4SF18's specific biological roles are still being elucidated, it has been implicated in tumorigenesis, where altered expression may influence cancer progression by modulating cell-cell communication and migration. Research into TM4SF18 aims to uncover its precise functions in health and disease, particularly its potential involvement in cancer biology and as a target for therapeutic interventions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AAB5; Transmembrane 4 L6 family member 18
基因别名: L6D; TM4SF18
UniProt ID: (Human) Q96CE8
Entrez Gene ID: (Human) 116441
