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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGDKIWLPFP VLLLAALPPV LLPGAAGFTP SLDSDFTFTL PAGQKECFYQ PMPLKASLEI EYQVLDGAGL DIDFHLASPE GKTLVFEQRK SDGVHTVETE VGDYMFCFDN TFSTISEKVI FFELILDNMG EQAQEQEDWK KYITGTDILD MKLEDILESI NSIKSRLSKS GHIQILLRAF EARDRNIQES NFDRVNFWSM VNLVVMVVVS AIQVYMLKSL FEDKRKSRT
The TMED5 gene encodes the transmembrane emp24 domain-containing protein 5, a member of the TMED family, which is involved in intracellular protein trafficking. This family is essential for the transport of proteins between the endoplasmic reticulum and the Golgi apparatus. TMED5 is a member of the γ subfamily and has been shown to regulate vital cellular processes, including protein secretion and signal transduction. Dysregulation of TMED5 has been implicated in various diseases, including hepatocellular carcinoma (HCC). Increased expression of TMED5 mRNA in HCC tissues is associated with poorer overall survival rates compared to normal tissues, suggesting its role in tumor progression and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: p24 family protein gamma-2; p24gamma2; p28; Transmembrane emp24 domain-containing protein 5
基因别名: CGI-100; TMED5; UNQ397/PRO733
Entrez Gene ID: (Human) 50999