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Invitrogen
TMED5 Polyclonal Antibody
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TMED5 Antibody (PA5-141055) in IHC (P)
Immunohistochemistry analysis of TMED5 in paraffin-embedded mouse large intestine tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with TMED5 Polyclonal antibody (Product # PA5-141055) using a dilution of 1:5,000 for 1 h... View More
产品信息
PA5-141055
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within Human TMED5 aa 1-200/229.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The TMED5 gene encodes the transmembrane emp24 domain-containing protein 5, a member of the TMED family, which is involved in intracellular protein trafficking. This family is essential for the transport of proteins between the endoplasmic reticulum and the Golgi apparatus. TMED5 is a member of the γ subfamily and has been shown to regulate vital cellular processes, including protein secretion and signal transduction. Dysregulation of TMED5 has been implicated in various diseases, including hepatocellular carcinoma (HCC). Increased expression of TMED5 mRNA in HCC tissues is associated with poorer overall survival rates compared to normal tissues, suggesting its role in tumor progression and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: p24 family protein gamma-2; p24gamma2; p28; Transmembrane emp24 domain-containing protein 5; transmembrane emp24 protein transport domain containing 5
基因别名: 3110020O18Rik; 4432412D15Rik; CGI-100; LRRG00120; p24g2; p28; TMED5; UNQ397/PRO733
UniProt ID: (Human) Q9Y3A6, (Rat) Q6AXN3, (Mouse) Q9CXE7
Entrez Gene ID: (Human) 50999, (Rat) 289883, (Mouse) 73130
