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Invitrogen
TMED7/TICAM2 Polyclonal Antibody
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产品信息
PA5151229
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
The immunogen is a synthetic peptide directed towards the middle region of human TMED7-TICAM2.
偶联物
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
TMED7/TICAM2 refers to two related genes. TMED7 encodes a protein involved in vesicular trafficking between the endoplasmic reticulum and Golgi, while TICAM2 (TRIF-related adaptor molecule, TRAM) encodes an adaptor protein in Toll-like receptor signaling, playing a role in innate immune responses, particularly in TLR4-mediated pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytoplasmic adaptor; MyD88-4; NF-kappa-B-activating protein 502; p24 family protein gamma-3; p24gamma3; p27; Putative NF-kappa-B-activating protein 502; TICAM-2; TIR domain-containing adapter molecule 2; TLR adapter molecule; toll like receptor adaptor molecule 2; Toll-like receptor adaptor protein 3; toll/interleukin-1 receptor (TIR) domain-containing adapter protein; Toll/interleukin-1 receptor domain-containing protein; Transmembrane emp24 domain-containing protein 7; transmembrane emp24 protein transport domain containing 7; TRIF-related adapter molecule; TRIF-related adaptor molecule; unnamed protein product
基因别名: CGI-109; MyD88-4; p24g3; p24gamma3; p27; Tag; TICAM-2; TICAM2; TIRAP3; TIRP; TMED7; TRAM
UniProt ID: (Human) Q86XR7, (Human) Q9Y3B3
Entrez Gene ID: (Human) 353376, (Human) 51014
immune system process
phagocytosis
inflammatory response
signal transduction
positive regulation of type I interferon production
toll-like receptor 4 signaling pathway
negative regulation of toll-like receptor 4 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
TRIF-dependent toll-like receptor signaling pathway
TRAM-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
response to other organism
cellular response to lipopolysaccharide
negative regulation of chemokine (C-C motif) ligand 5 production
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of interleukin-18-mediated signaling pathway
intracellular protein transport
ER to Golgi vesicle-mediated transport
Golgi organization
protein transport
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