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Invitrogen
TMEM255B Polyclonal Antibody
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TMEM255B Antibody (PA5-144063) in IHC (P)
Immunohistochemistry analysis of TMEM255B in paraffin-embedded section of rat intestine tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with TMEM255B Polyclonal antibody (Product # PA5-144063) using a dilution of 1 μg/mL overnight at 4°C. Biotinylated goat anti-rabbit IgG was... View More
产品信息
PA5-144063
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived mouse Tmem255b recombinant protein (Position: Q196-L240).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.01mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: mouse heart tissue, mouse testis tissue, mouse lung tissue. IHC: rat lung tissue, rat intestine tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The TMEM255B gene encodes a member of the transmembrane protein family, which are proteins that span biological membranes and have been suggested to have roles in cellular signaling and structure. TMEM255B has been studied for its expression in different cancer types, where it acts as a potential marker. Specifically, it has been observed in serous cystic neoplasms (SCNs) and other neoplasms, with a noteworthy frequency in gastric-type intraductal papillary mucinous neoplasms (IPMNs) and pancreatic ductal adenocarcinomas (PDACs). The expression of TMEM255B in these neoplasms indicates its potential as a diagnostic marker and may reflect its involvement in cancer biology. While its functions are still being elucidated, TMEM255B's role in cancer highlights its significance in tumor progression and potential as a target for further investigation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: family with sequence similarity 70, member B; Protein FAM70B; Transmembrane protein 255B
基因别名: Fam70b; Gm687; RGD1566042; Tmem255b
UniProt ID: (Mouse) Q5FW56
Entrez Gene ID: (Mouse) 272465, (Rat) 290877
