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Invitrogen
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Immunogen sequence: VPLSQLAYGP AVPPQTLYNP AQQILAYAGF RLTPEPVPTC SSYPLPLQPC SRFPVAPSSA LASSEDLQPP SPSSSGSGLP GQAPPCYAP
Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 53%.
The TMEM255B gene encodes a member of the transmembrane protein family, which are proteins that span biological membranes and have been suggested to have roles in cellular signaling and structure. TMEM255B has been studied for its expression in different cancer types, where it acts as a potential marker. Specifically, it has been observed in serous cystic neoplasms (SCNs) and other neoplasms, with a noteworthy frequency in gastric-type intraductal papillary mucinous neoplasms (IPMNs) and pancreatic ductal adenocarcinomas (PDACs). The expression of TMEM255B in these neoplasms indicates its potential as a diagnostic marker and may reflect its involvement in cancer biology. While its functions are still being elucidated, TMEM255B's role in cancer highlights its significance in tumor progression and potential as a target for further investigation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: family with sequence similarity 70, member B; Protein FAM70B; Transmembrane protein 255B
基因别名: FAM70B; TMEM255B
UniProt ID: (Human) Q8WV15
Entrez Gene ID: (Human) 348013