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Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell cycle control protein 50B; P4-ATPase flippase complex beta subunit TMEM30B; Transmembrane protein 30B
基因别名: CDC50B; TMEM30B
UniProt ID: (Human) Q3MIR4
Entrez Gene ID: (Human) 161291