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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total TMPRSS11F protein.
TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Airway trypsin-like protease 4; Transmembrane protease serine 11F; transmembrane protease, serine 11F; unnamed protein product
基因别名: 4631408C20; 4732406D01Rik; HATL4; TMPRSS11F
UniProt ID: (Human) Q6ZWK6, (Mouse) Q8BHM9
Entrez Gene ID: (Human) 389208, (Mouse) 243083