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Invitrogen
TMPRSS2 Polyclonal Antibody
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产品信息
PA5-96019
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 140-400 of human TMPRSS2.
偶联物
形式
Liquid
浓度
1.02 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: GLLWKFMGSK CSNSGIECDS SGTCINPSNW CDGVSHCPGG EDENRCVRLY GPNFILQVYS SQRKSWHPVC QDDWNENYGR AACRDMGYKN NFYSSQGIVD DSGSTSFMKL NTSAGNVDIY KKLYHSDACS SKAVVSLRCI ACGVNLNSSR QSRIVGGESA LPGAWPWQVS LHVQNVHVCG GSIITPEWIV TAAHCVEKPL NNPWHWTAFA GILRQSFMFY GAGYQVEKVI SHPNYDSKTK NNDIALMKLQ KPLTFNDLVK P; Positive Samples: 22Rv1; Cellular Location: Cell membrane, Single-pass type II membrane protein
靶标信息
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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