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Positive Samples: U-251MG, HeLa, HepG2, A-549, Mouse liver, Mouse brain, Rat testis
Immunogen sequence: KPPLYMGPEY IKYFNDKTID EELERDKRVT WIVEFFANWS NDCQSFAPIY ADLSLKYNCT GLNFGKVDVG RYTDVSTRYK VSTSPLTKQL PTLILFQGGK EAMRRPQIDK KGRAVSWTFS EENVIREFNL NELYQRAKKL SKAGDNIPEE QPVASTPTTV SDGENKKDK
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell proliferation-inducing gene 26 protein; growth-inhibiting gene 11; protein disulfide isomerase family A, member 12; thioredoxin domain containing 14; Thioredoxin domain-containing protein 14; Thioredoxin-related transmembrane protein 2
基因别名: 2310042M24Rik; AA589631; CGI-31; My009; PDIA12; PIG26; PSEC0045; TMX2; TXNDC14; UNQ237/PRO270
UniProt ID: (Human) Q9Y320, (Rat) Q5XIK2, (Mouse) Q9D710
Entrez Gene ID: (Human) 51075, (Rat) 295701, (Mouse) 66958