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Abnova
TNFAIP8 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00025816-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TNFAIP8 (NP_055165.1, 1 a.a. approximately 190 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.42 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAVATDVFNS KNLAVQAQKK ILGKMVSKSI ATTLIDDTSS EVLDELYRVT REYTQNKKEA EKIIKNLIKT VIKLAILYRN NQFNQDELAL MEKFKKKVHQ LAMTVVSFHQ VDYTFDRNVL SRLLNECREM LHQIIQRHLT AKSHGRVNNV FDHFSDCEFL AALYNPFGNF KPHLQKLCDG INKMLDEENI
靶标信息
TNFalpha-IP 8 (tumor necrosis factor, alpha-induced protein 8), also known as NFkappa B-inducible DED-containing protein (NDED), SCC-S2 or TNF-induced protein GG2-1, is a 198 amino acid cytoplasmic protein induced by NFkappa B and TNF. The induction of TNFalpha-IP 8 by TNF is dependent on the activation of NFkappa B. TNFalpha-IP 8 negatively mediates apoptosis and may also play a role in tumor progression. TNFalpha-IP 8 specifically inhibits caspase-8 activity, which results in the inhibition of BID cleavage and caspase-3 activation during TNF-mediated apoptosis. TNFalpha-IP 8 is expressed at high levels in thymus, bone marrow, lymph node, spleen, thyroid, placenta and various tumor tissues, as well as fetal lung, liver and kidney. TNFalpha-IP 8 is present as three isoforms produced by alternative splicing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Head and neck tumor and metastasis-related protein; MDC-3.13; MDC3.13; NDED; NF-kappa-B-inducible DED-containing protein; SCC S2; SCC-S2; TNF alpha-induced protein 8; TNF-induced protein GG2-1; TNFalpha IP8; TNFalpha-IP 8; TNFalphaIP8; Tumor necrosis factor alpha-induced protein 8
基因别名: TNFAIP8
Entrez Gene ID: (Human) 25816
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
