Abnova

TNIK Polyclonal Antibody, MaxPab™

Name: TNIK Polyclonal Antibody, MaxPab\u2122
Brand: Abnova
SKU: H00023043-D01P

查看其他17个TNIK抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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TNIK Antibody (H00023043-D01P) in WB

Western Blot analysis of TNIK expression in transfected 293T cell line by TNIK MaxPab polyclonal antibody. Lane 1: TNIK transfected lysate(60.30 KDa). Lane 2: Non-transfected lysate. .

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产品信息

H00023043-D01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

TNIK (AAH55427.1, 1 a.a. approximately 538 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MKKVTDYSSS SEESESSEEE EEDGESETHD GTVAVSDIPR LIPTGAPGSN EQYNVGMVGT HGLETSHADS FSGSISREGT LMIRETSGEK KRSGHSDSNG FAGHINLPDL VQQSHSPAGT PTEGLGRVST HSQEMDSGTE YGMGSSTKAS FTPFVDPRVY QTSPTDEDEE DEESSATALF TSELLRQEQA KLNEARKISV VNVNPTNIRP HSDTPEIRKY KKRFNSEILC AALWGVNLLV GTENGLMLLD RSGQGKVYNL INRRRFQQMD VLEGLNVLVT ISGKKNKLRV YYLSWLRNRI LHNDPEVEKK QGWITVGDLE GCIHYKVVKY ERIKFLVIAL KNAVEIYAWA PKPYHKFMAF KSFADLQHKP LLVDLTVEEG QRLKVIFGSH TGFHVIDVDS GNSYDIYIPS HIQGNITPHA IVILPKTDGM EMLVCYEDEG VYVNTYGRIT KDVVLQWGEM PTSVAYIHSN QIMGWGEKAI EIRSVETGHL DGVFMHKRAQ RLKFLCERND KVFFASVRSG GSSQVFFMTL NRNSMMNW

靶标信息

TNIK or TRAF2 and NCK interacting kinase is characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function. TNIK is mainly expression in brain, heart, and spleen and it is a specific effector of RAP2 which regulate actin cytoskeleton. TNIK is autophosphorylated in a manner dependent upon lys54 in the ATP-binding pocket of its kinase domain and plays a main role in cytoskeleton regulation. TNIK has also been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton.

仅用于科研。不用于诊断过程。未经明确授权不得转售。