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TNNC1 Monoclonal Antibody (1F8-A9)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00007134-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1F8-A9
抗原
TNNC1 (AAH30244, 1 a.a. approximately 161 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.48 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVMRMLGQ NPTPEELQEM IDEVDEDGSG TVDFDEFLVM MVRCMKDDSK GKSEEELSDL FRMFDKNADG YIDLDELKIM LQATGETITE DDIEELMKDG DKNNDGRIDY DEFLEFMKGV E
靶标信息
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiac 3; cardiac troponin C; Cardiac troponin I; CMD1FF; CMD2A; CMH7; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; Tn1; Tni; TNN I3; TNNC 1; TNNC1; TNNI3; troponin C type 1 (slow); Troponin I; Troponin I cardiac; TroponinI; unnamed protein product
基因别名: CMD1Z; CMH13; TN-C; TNC; TNNC
UniProt ID: (Human) P63316
Entrez Gene ID: (Human) 7134
diaphragm contraction
skeletal muscle contraction
regulation of muscle contraction
response to metal ion
muscle filament sliding
negative regulation of ATPase activity
regulation of muscle filament sliding speed
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
cardiac muscle cell contraction
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
