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Abnova
TP53BP2 Monoclonal Antibody (1A10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00007159-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1A10
抗原
TP53BP2 (AAH58918, 511 a.a. approximately 610 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: PYFGQTNQPP SDIKPDGSSQ QLSTVVPSMG TKPKPAGQQP RVLLSPSIPS VGQDQTLSPG SKQESPPAAA VRPFTPQPSK DTLLPPFRKP QTVAASSIYS
靶标信息
Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 53BP2; Apoptosis-stimulating of p53 protein 2; Bbp; Bcl2-binding protein; P PPP1R13A; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2
基因别名: ASPP2; BBP; TP53BP2
Entrez Gene ID: (Human) 7159
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