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Invitrogen
TP53I11 Polyclonal Antibody
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TP53I11 Antibody (PA5-88810) in IHC (P)
Immunohistochemistry analysis of TP53I11 in paraffin-embedded human lymph node tumors. Samples were incubated with TP53I11 Polyclonal antibody (Product # PA5-88810) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-88810
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human TP53I11 (NP_0012452491)
偶联物
形式
Liquid
浓度
2.69 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MAAKQPPPLM KKHSQTDLVS RLKTRKILGV GGEDDDGEVH RSKISQVLGN EIKFTIREPL GLRVWQFVSA; Positive Samples: HeLa, Mouse brain; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: p53-induced gene 11 protein; transformation related protein 53 inducible protein 11; Tumor protein p53-inducible protein 11
基因别名: PIG11; TP53I11; Trp53i11
UniProt ID: (Human) O14683, (Rat) B3DMA0
Entrez Gene ID: (Human) 9537, (Rat) 311209
