Abnova

TP53RK Monoclonal Antibody (3H4)

Name: TP53RK Monoclonal Antibody (3H4)
Brand: Abnova
SKU: H00112858-M07
Price: 6404.00 CNY
Availability: InStock

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说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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TP53RK Antibody (H00112858-M07) in ELISA

Detection limit for recombinant GST tagged TP53RK is approximately 0.1 ng/mL as a capture antibody.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

Immunogen image

Immunogen Image TP53RK Monoclonal Antibody (3H4)

产品信息

H00112858-M07

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

3H4

抗原

TP53RK (AAH09727, 154 a.a. approximately 253 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Sandwich ELISA (Recombinant protein).

Immunogen sequence: HDEDLIHGDL TTSNMLLKPP LEQLNIVLID FGLSFISALP EDKGVDLYVL EKAFLSTHPN TETVFEAFLK SYSTSSKKAR PVLKKLDEVR LRGRKRSMVG

靶标信息

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914). TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806). [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。