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Invitrogen
TRABD2A Monoclonal Antibody (901705)
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产品信息
MA5-61944
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
901705
抗原
Chinese hamster ovary cell line CHO-derived recombinant human Tiki1/TRABD2A, Met1-Met477
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Metalloprotease TIKI1; TRAB domain-containing protein 2A; UPF0632 protein C2orf89
基因别名: C2orf89; TIKI1; TRABD2A
UniProt ID: (Human) Q86V40
Entrez Gene ID: (Human) 129293
