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This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Tax1 (human T-cell leukemia virus type I) binding protein 1; Tax1-binding protein 1; TRAF6-binding protein
基因别名: CALCOCO3; PRO0105; T6BP; TAX1BP1; TXBP151
UniProt ID: (Human) Q86VP1
Entrez Gene ID: (Human) 8887