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Invitrogen
TRAPPC5 Polyclonal Antibody
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产品信息
PA5-104182
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TRAPPC5(Accession Q8IUR0), corresponding to amino acid residues T80-V130.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total TRAPPC5.
靶标信息
TRAPPC5 (trafficking protein particle complex 5), also known as TRS31, is a 181 amino acid protein belonging to the TRAPP (transport protein particle) small subunits family and the BET3 subfamily. Encoded by a gene that maps to human chromosome 19p13.2, TRAPPC5 is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. Evolutionarily conserved, TRAPPC5 plays a role in protein binding,vesicle-mediated transport and nucleotide exchange stimulation. TRAPPC5 also performs guanine nucleotide exchanger factor (GEF) functions both in vitro and in vivo. Localizing to the Golgi apparatus, TRAPPC5 is essential for endoplasmic reticulum (ER)-to-Golgi and intra-Golgi vesicle trafficking in yeast, as well as additional transport events in mammals, such as post-Golgi trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Trafficking protein particle complex subunit 5
基因别名: 4021401A16Rik; RGD1563971; TRAPPC5; TRS31
UniProt ID: (Human) Q8IUR0, (Mouse) Q9CQA1
Entrez Gene ID: (Human) 126003, (Mouse) 66682, (Rat) 363858
