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Alomone Labs, LTD
TRHR1 Polyclonal Antibody
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TRHR1 Antibody (ATR-005-200UL) in ICC/IF
Expression of Thyrotropin-releasing hormone receptor 1 in mouse MS1 cells - Immunocytochemical staining of mouse pancreatic islet endothelial (MS1) cells. Cells were stained using Anti-TRHR1 Antibody (#ATR-005) followed by goat- Anti-rabbit-AlexaFluor-594 secondary Antibody (red). Nuclear staining was demonstrated using DAPI as the counterstain (blue).
产品信息
ATR-005-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CKQKPTEKAANYS, corresponding to amino acid residues 336-349 of rat Thyrotropin-releasing hormone receptor 1, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.75 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH. Reports suggest that TRH-R is a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking. It is known to widely express in the thyrotroph cells of the anterior pituitary.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC141920; Thyroliberin receptor; Thyrotropin-releasing hormone receptor; TRH receptor; TRH-R; TRH1 Receptor
基因别名: TRH-R; TRH-R1; TRHR
UniProt ID: (Human) P34981, (Rat) Q01717, (Mouse) P21761
Entrez Gene ID: (Human) 7201, (Rat) 25570, (Mouse) 22045
