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Invitrogen
TRIM15 Polyclonal Antibody
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产品信息
PA5-40946
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human TRIM15 (aa 141-190).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: RDEIEDVKCQ EDQKLQVLLT QIESKKHQVE TAFERLQQEL EQQRCLLLAR
Sequence homology: Cow: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 79%; Rat: 86%
靶标信息
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: E3 ubiquitin-protein ligase TRIM15; RING finger protein 93; tripartite motif-containing 15; Zinc finger protein 178; Zinc finger protein B7
基因别名: RNF93; TRIM15; ZNF178; ZNFB7
UniProt ID: (Human) Q9C019
Entrez Gene ID: (Human) 89870
mesodermal cell fate determination
positive regulation of type I interferon production
innate immune response
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
positive regulation of RIG-I signaling pathway
negative regulation of intracellular transport of viral material
negative regulation of viral release from host cell
