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Invitrogen
TRIM37 Polyclonal Antibody
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TRIM37 Antibody (PA5-30094) in WB
Western Blot using TRIM37 Polyclonal Antibody (Product # PA5-30094). Sample (30 µg of whole cell lysate). Lane A: Jurkat. Lane B: Raji. Lane C: K562. Lane D: NCI-H929. 7.5% SDS PAGE. TRIM37 Polyclonal Antibody (Product # PA5-30094) diluted at 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
PA5-30094
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the N-terminus region of human TRIM37. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: Jurkat, Raji, K562, NCI-H929, Rat2.
Predicted reactivity: Human (99%), Mouse (99%), Rat (99%), Chicken (98%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate (PIP). PI4KB may regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase TRIM37; Mulibrey nanism protein; RING-B-box-coiled-coil protein; RING-type E3 ubiquitin transferase TRIM37; tripartite motif protein 37; Tripartite motif-containing protein 37
基因别名: KIAA0898; MUL; POB1; TEF3; TRIM37
UniProt ID: (Human) O94972
Entrez Gene ID: (Human) 4591, (Rat) 360592
chromatin binding
ubiquitin-protein transferase activity
tumor necrosis factor receptor binding
protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase binding
protein homodimerization activity
ubiquitin protein ligase activity
molecular_function
ubiquitin-protein ligase
protein modifying enzyme
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of NF-kappaB transcription factor activity
histone H2A monoubiquitination
histone H2A-K119 monoubiquitination
negative regulation of centriole replication
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
aggresome assembly
biological_process
