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Invitrogen
TRIM67 Polyclonal Antibody
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TRIM67 Antibody (PA5-144056) in WB
Western blot analysis of TRIM67 using TRIM67 antibody (Product # PA5-144056). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human HepG2 whole cell lysates; Lane 2: human A549 whole cell lysates; Lane 3: human Caco-2 whole cell lysates; Lane 4: rat C6 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Bloc... View More
产品信息
PA5-144056
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human TRIM67 recombinant protein (Position: H24-D545).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human HepG2 whole cell, human A549 whole cell, human Caco-2 whole cell, rat C6 whole cell. Flow: HEL cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The TRIM67 gene encodes a member of the tripartite motif (TRIM) protein family, which is involved in various cellular processes including protein ubiquitination, signal transduction, and immune responses. TRIM67 contains RING, B-box, and coiled-coil domains, characteristic of TRIM proteins, which facilitate interactions with other proteins and contribute to its role in ubiquitination and cellular regulation. TRIM67 is notably expressed in the brain and has been associated with neurodevelopmental processes, particularly influencing neuronal differentiation and synapse formation. This gene plays a regulatory role in signaling pathways that are critical for neural development, and mutations or dysregulation in TRIM67 have been linked to neurodevelopmental disorders and cognitive deficits. Additionally, TRIM67's involvement in protein degradation and signal modulation may impact cellular architecture and brain function. Ongoing research seeks to elucidate TRIM67's precise mechanisms and potential therapeutic targets for neurological conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: TRIM9-like protein; TRIM9-like protein TNL; Tripartite motif-containing protein 67
基因别名: RGD1560667; TNL; TRIM67
UniProt ID: (Human) Q6ZTA4
Entrez Gene ID: (Human) 440730, (Rat) 307938
