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Invitrogen
TROY Recombinant Rabbit Monoclonal Antibody (1R8Y5)
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TROY Antibody (MA5-37871) in WB
Western blot analysis of TROY in extracts of various cell lines. Samples were incubated with TROY Monoclonal antibody (Product # MA5-37871) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
MA5-37871
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1R8Y5
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human TROY/TNFRSF19 (Q9NS68)
偶联物
形式
Liquid
浓度
1.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: 22Rv1, Raji, U-251MG, Mouse lung, Mouse brain, Mouse spleen, Rat lung, Rat brain
Immunogen sequence: RFQKANCSAT SDAICGDCLP GFYRKTKLVG FQDMECVPCG DPPPPYEPHC ASKVNLVKIA STASSPRDTA LAAVICSALA TVLLALLILC VIYCKRQFME K
靶标信息
Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Toxicity and JNK inducer; TRADE; Tumor necrosis factor receptor superfamily member 19; tumor necrosis factor receptor superfamily, member 19
基因别名: AL023044; AW123854; RGD1564996; TAJ; TAJ-ALPHA; TNFRSF19; TRADE; TROY; UNQ1888/PRO4333
UniProt ID: (Human) Q9NS68, (Mouse) Q9JLL3
Entrez Gene ID: (Human) 55504, (Rat) 290300, (Mouse) 29820
