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Invitrogen
TRPC4AP Polyclonal Antibody
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TRPC4AP Antibody (PA5-106444) in IHC (P)
Immunohistochemistry analysis of TRPC4AP in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with TRPC4AP polyclonal antibody (Product # PA5-106444) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-106444
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TRPC4AP(Accession Q8TEL6), corresponding to amino acid residues V6-Q56.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total TRPC4AP.
靶标信息
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: protein phosphatase 1, regulatory subunit 158; Protein TAP1; Protein TRUSS; Rabex-5/Rin2-interacting protein; short transient receptor potential channel 4 associated protein; Short transient receptor potential channel 4-associated protein; TAP1 protein; TNF-receptor; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP; transient receptor potential cation channel, subfamily C, member 4 associated protein; transient receptor protein 4, associated protein; TRP4-associated protein; Trp4-associated protein TAP1; trpc4-associated protein; tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein
基因别名: 4833429F06Rik; C20orf188; D2Ertd113e; mFLJ00177; PPP1R158; TRPC4AP; TRRP4AP; TRUSS
UniProt ID: (Human) Q8TEL6, (Mouse) Q9JLV2
Entrez Gene ID: (Human) 26133, (Rat) 362247, (Mouse) 56407
