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1 µg/mL of MA5-45476 was sufficient for detection of TrpC7 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.| Detects approximately 100kDa.
TRPC7 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC7 is probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. TRPC7 is also activated by diacylglycerol (DAG). Further, TRPC7 may also be activated by intracellular calcium store depletion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: capacitative calcium channel TRPC7; hTRP7; likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7; mTRP7; putative capacitative calcium channel; Short transient receptor potential channel 7; transient receptor potential cation channel, subfamily C, member 7; Transient receptor protein 7; TRP-7; TRP7 protein; TrpC7
基因别名: TRP7; TRPC7; Trrp8
UniProt ID: (Human) Q9HCX4, (Mouse) Q9WVC5
Entrez Gene ID: (Human) 57113, (Rat) 282822, (Mouse) 26946
分子生物学功能: ion channel transporter