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Invitrogen
TRPM5 Polyclonal Antibody
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TRPM5 Antibody (PA5-88498) in WB
Western blot analysis of TRPM5 in extracts of various cell lines. Samples were incubated with TRPM5 Polyclonal antibody (Product # PA5-88498) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-88498
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1026-1165 of human TRPM5 (NP_0553701)
偶联物
形式
Liquid
浓度
1.84 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RVFKKEAEHK REHLERDLPD PLDQKVVTWE TVQKENFLSK MEKRRRDSEG EVLRKTAHRV DFIAKYLGGL REQEKRIKCL ESQINYCSVL VSSVADVLAQ GGGPRSSQHC GEGSQLVAAD HRGGLDGWEQ PGAGQPPSDT; Positive Samples: U-87MG, Mouse liver, Mouse brain; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
This gene encodes a member of the transient receptor potential protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Caions. It is activated by lower concentrations of intracellular Ca, and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15. 5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Long transient receptor potential channel 5; long transient receptor potential-related channel 5; LTrpC-5; MLSN1 and TRP-related; MLSN1- and TRP-related gene 1 protein; Transient receptor potential cation channel subfamily M member 5; transient receptor potential cation channel, subfamily M, member 5; TRPM5
基因别名: 9430099A16Rik; LTrpC-5; LTRPC5; MTR1; TRPM5
UniProt ID: (Human) Q9NZQ8, (Mouse) Q9JJH7
Entrez Gene ID: (Human) 29850, (Mouse) 56843
