NeoBiotechnologies

TRPS1 (Transcriptional repressor GATA binding 1) Recombinant Rabbit Monoclonal Antibody (MSVA-512R)

Name: TRPS1 (Transcriptional repressor GATA binding 1) Recombinant Rabbit Monoclonal Antibody (MSVA-512R)
Brand: NeoBiotechnologies
SKU: 7227-RBM13-P1

查看其他17个TRPS1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

TRPS1 (Transcriptional repressor GATA binding 1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TRPS1 (Transcriptional repressor GATA binding 1) Antibody (7227-RBM13-P1) in IHC (P)

Zinc finger transcription factor Trps1 Rabbit Recombinant Monoclonal Antibody (MSVA-512R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.

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Immunogen image

Immunogen Image TRPS1 (Transcriptional repressor GATA binding 1) Recombinant Rabbit Monoclonal Antibody (MSVA-512R)

产品信息

7227-RBM13-P1

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:100-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG, kappa

Expression System

CHO cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

MSVA-512R

抗原

Recombinant fragment (around aa 900-1100) of human TRPS1 protein (exact sequence is proprietary).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A

保存液

PBS with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4°C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product cellular localization: Centrosome, Cytoplasm, Cytoskeleton, Endoplasmic reticulum, Microtubule organizing center, Mitochondrion matrix, Nucleus, PML body.

Positive control: Tonsil: More than 20 % of germinal centre B-cells must show a weak to moderate nuclear staining.

Tissue specificity: Ubiquitous. Isoforms are expressed in a wide range of normal tissues but in a tissue-dependent manner. Isoform 2 is expressed in most normal tissues but is not detected in brain, lung, prostate, muscle, fetal brain, spinal cord and fetal liver. Isoform 3 is expressed in most normal tissues but is not detected in lung, spleen, testis, fetal brain, spinal cord and fetal liver. Isoform 7 is expressed in most normal tissues but is not detected in prostate, uterus, skeletal muscle and breast. Isoform 8 is detected only in colon, bone marrow, testis, fetal brain and intestine. Isoform 9 is expressed in most normal tissues but is not detected in brain, heart, lung, fetal liver, salivary gland, breast or intestine.

靶标信息

This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq].

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Tricho-rhino-phalangeal syndrome type I protein; trichorhinophalangeal syndrome I; Zinc finger protein GC79; Zinc finger transcription factor Trps1

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基因别名: GC79; LGCR; TRPS1

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UniProt ID: (Human) Q9UHF7

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Entrez Gene ID: (Human) 7227

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功能

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding zinc ion binding DNA-binding transcription factor

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