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Bethyl Laboratories
TSN Polyclonal Antibody
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TSN Antibody (A305-374A) in WB
Detection of human and mouse TSN by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-TSN antibody (Product # A305-374A) (lot A305-374A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
产品信息
A305-374A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 150 to 200 of Human Translin.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
靶标信息
Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C3PO; Component 3 of promoter of RISC; recombination hotspot associated factor; recombination hotspot-binding protein; TB-RBP; testis brain-RNA binding protein; Testis/brain RNA-binding protein; testis/brain-RNA-binding protein; Translin
基因别名: 2610034C24Rik; AU040286; BCLF-1; C3PO; RCHF1; REHF-1; TB-RBP; TBRBP; TRSLN; TSN
UniProt ID: (Human) Q15631, (Mouse) Q62348
Entrez Gene ID: (Human) 7247, (Mouse) 22099
DNA binding
mRNA binding
endonuclease activity
protein binding
sequence-specific DNA binding
single-stranded DNA binding
RNA binding
nuclease activity
endoribonuclease activity
hydrolase activity
protein complex binding
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
