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Abnova
TSSK6 Polyclonal Antibody, MaxPab™
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TSSK6 Antibody (H00083983-D01P) in WB
Western Blot analysis of TSSK6 expression in transfected 293T cell line (H00083983-T02) by TSSK6 MaxPab polyclonal antibody.
Lane 1: TSSK6 transfected lysate(30.30 KDa).
Lane 2: Non-transfected lysate.
Lane 1: TSSK6 transfected lysate(30.30 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00083983-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TSSK6 (NP_114426.1, 1 a.a. approximately 273 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MSGDKLLSEL GYKLGRTIGE GSYSKVKVAT SKKYKGTVAI KVVDRRRAPP DFVNKFLPRE LSILRGVRHP HIVHVFEFIE VCNGKLYIVM EAAATDLLQA VQRNGRIPGV QARDLFAQIA GAVRYLHDHH LVHRDLKCEN VLLSPDERRV KLTDFGFGRQ AHGYPDLSTT YCGSAAYASP EVLLGIPYDP KKYDVWSMGV VLYVMVTGCM PFDDSDIAGL PRRQKRGVLY PEGLELSERC KALIAELLQF SPSARPSAGQ VARNCWLRAG DSG
靶标信息
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cancer/testis antigen 72; CT72; serine/threonine protein kinase SSTK; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase; testis secretory sperm-binding protein Li 205a; testis-specific serine kinase 6; Testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK6
基因别名: CT72; FKSG82; SSTK; TSSK4; TSSK6
UniProt ID: (Human) Q9BXA6
Entrez Gene ID: (Human) 83983
