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Invitrogen
TTC40 Polyclonal Antibody
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产品信息
PA5-58104
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LAPDAFQIVL DSENEAKVST GKNRGRFTYL CAKAWHHTVS VDKAAGHLRR LGNENDKERI QIWAELAKVA RKQ
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.
靶标信息
The TTC40 gene, which stands for Tetratricopeptide repeat domain 40, is a member of the TPR protein family characterized by highly conserved motifs that facilitate protein-protein interactions. This gene plays a significant role in various cellular processes, including signal transduction and protein assembly. TTC40 has been identified as a novel methylated gene in nasopharyngeal carcinoma, where its expression is significantly reduced in tumor tissues due to hypermethylation. This epigenetic alteration suggests a potential role of TTC40 in tumorigenesis, possibly acting as a tumor suppressor. The decreased expression of TTC40 in cancerous tissues highlights its importance in maintaining cellular homeostasis and integrity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cilia- and flagella-associated protein 46; protein CFAP46; tetratricopeptide repeat domain 40; Tetratricopeptide repeat protein 40; TPR repeat-containing protein C10orf93
基因别名: bA288G11.4; bA288G11.5; bB137A17.2; bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93; CFAP46; TTC40
UniProt ID: (Human) Q8IYW2
Entrez Gene ID: (Human) 54777
