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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The DNA replication (origin) licensing system is necessary for duplicating the genome in each cell cycle. Geminin is a protein that prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during G1 phase and accumulates during S, G2, and M phases of mitosis. It is then degraded during the metaphase-anaphase trasition allowing replication to occur during subsequent cycles. Geminin has also been implicated in maintaining integrity of the male germline genome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ23263; Tel2 interacting protein 2 homolog; TELO2-interacting protein 2; unnamed protein product
基因别名: C8orf41; MRT39; RGD1310414; TTI2
UniProt ID: (Human) Q6NXR4, (Rat) Q66H56
Entrez Gene ID: (Human) 80185, (Rat) 290811