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Invitrogen
TUBA3C Recombinant Rabbit Monoclonal Antibody (PSH0-14)
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TUBA3C Antibody (MA5-50778) in IHC (P)
Immunohistochemistry of TUBA3C in paraffin-embedded mouse testis tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with TUBA3C recombinant monoclonal antibody (Product # MA5-50778) with a dilution of 1:2,000 for 1 hour at roo... View More
产品信息
MA5-50778
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH0-14
抗原
Recombinant protein within human TUBA3C aa 150-350/450.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive control: 293T cell lysate, A431 cell lysate, HepG2 cell lysate, 293 cell lysate, Hela cell lysate, Jurkat cell lysate, SH-SY5Y cell lysate, human testis tissue.
Predicted band size: 50 kDa
Subcellular Location: Cytoplasm, cytoskeleton.
靶标信息
The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). Microtubules have their intrinsic polarity; highly dynamic plus ends and less dynamic minus ends. Microtubules are required for vital processes in eukaryotic cells including mitosis, meiosis, maintenance of cell shape and intracellular transport. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs).The GTP (guanosintriphosphate) molecule is an essential for tubulin heterodimer to associate with other heterodimers to form microtubule. In vivo, microtubule dynamics vary considerably. Microtubule polymerization is reversible and a populations of microtubules in cells are on their minus ends either growing or shortening - this phenomenon is called dynamic instability of microtubules. The alpha-tubulin (relative molecular weight around 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha tubulin 3C; Alpha-tubulin 2; Alpha-tubulin 3C; alpha-tubulin 3C/D; Tubulin alpha-2 chain; Tubulin alpha-3C chain; tubulin, alpha 2; tubulin, alpha 3c
基因别名: bA408E5.3; TUBA2; TUBA3C
UniProt ID: (Human) Q6PEY3
Entrez Gene ID: (Human) 7278
