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Invitrogen
TXNDC3 Polyclonal Antibody
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TXNDC3 Antibody (PA5-120532) in WB
Western blot analysis of TXNDC3 in extracts of various cell lines. Samples were incubated with TXNDC3 Polyclonal antibody (Product # PA5-120532) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-120532
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 299-588 of human NME8 (NP_057700.3).
偶联物
形式
Liquid
浓度
3.59 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: U-87MG, SH-SY5Y, Jurkat.
Immunogen sequence: FMDAFFPDFK KMKSMKLEKT LALLRPNLFH ERKDDVLRII KDEDFKILEQ RQVVLSEKEA QALCKEYENE DYFNKLIENM TSGPSLALVL LRDNGLQYWK QLLGPRTVEE AIEYFPESLC AQFAMDSLPV NQLYGSDSLE TAEREIQHFF PLQSTLGLIK PHATSEQREQ ILKIVKEAGF DLTQVKKMFL TPEQIEKIYP KVTGKDFYKD LLEMLSVGPS MVMILTKWNA VAEWRRLMGP TDPEEAKLLS PDSIRAQFGI SKLKNIVHGA SNAYEAKEVV NRLFEDPEEN
靶标信息
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'-5' exonuclease NME8; epididymis secretory protein Li 99; NM23-H8; NME/NM23 family member 8; sperm-specific thioredoxin 2; Spermatid-specific thioredoxin-2; Sptrx-2; thioredoxin domain containing 3 (spermatozoa); Thioredoxin domain-containing protein 3
基因别名: 1700056P15Rik; CILD6; HEL-S-99; NM23-H8; NME8; Sptrx-2; SPTRX2; TXNDC3
UniProt ID: (Human) Q8N427, (Mouse) Q715T0
Entrez Gene ID: (Human) 51314, (Mouse) 73412
nucleoside diphosphate phosphorylation
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
multicellular organism development
spermatogenesis
cell differentiation
sperm motility
cellular response to reactive oxygen species
cilium assembly
cell redox homeostasis
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
