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Invitrogen
Tafolecimab Recombinant Human Monoclonal Antibody
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Tafolecimab Antibody (MA5-42291) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human PCSK9 protein expressed in CHO cells using a Tafolecimab biosimilar monoclonal antibody (Product # MA5-42291). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-42291
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG2, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human PCSK9
偶联物
形式
Liquid
浓度
1.02 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
GPRC5D/CD3 bispecific antibody is used to treat multiple myeloma. The bispecific antibody is generically named tafolecimab. It is constructed using the Duobody technology authorized by Genmab. The heavy chain of the anti-CD3 antibody is introduced into F405L and R409K to construct the double antibody. S228P, F234A, and L235A mutations were also introduced into the IgG4 constant region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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