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Invitrogen
Thimet Oligopeptidase Monoclonal Antibody (4D6)
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产品信息
MA5-24783
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
4D6
抗原
A synthetic peptide corresponding to residues 56-72 of human Thimet Oligopeptidase.
偶联物
形式
Liquid
浓度
1.54 mg/mL
纯化类型
Protein A
保存液
TBS
内含物
0.05% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 3.4.24; EC 3.4.24.15; Endo-oligopeptidase A; Endopeptidase 24.15; metalloendopeptidase; MP78; PZ-peptidase; Soluble metallo-endopeptidase; Thimet oligopeptidase
基因别名: AI131655; AI327041; EP24.15; MEPD_HUMAN; MP78; THOP1; TOP
UniProt ID: (Human) P52888, (Mouse) Q8C1A5, (Rat) P24155
Entrez Gene ID: (Human) 7064, (Mouse) 50492, (Rat) 64517
