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Immunogen sequence: HQDKDTTFDL FSISNINRKT IGAKQFRGPD PGVPAYRFVR FDYIPPVNAD DLSKITKIMR QKEGFFLTAQ LKQDGKSRGT LLALEGPGLS QRQFEIVSNG PADTLDLTYW IDGTRHVVSL EDVGLADSQW KNVTVQVAGE TYSLHVGCDL IDSFALDEPF YEHLQAEKSR MYVAKGSARE SHFRGLLQNV HLVFENSVED ILSKKGCQQG QGAEINAISE NTETLRLGPH VTTEYVGPSS ERRPEVCERS CEELGNMVQE L; Positive Samples: Mouse heart, Rat heart
The Thrombospondin proteins (TSP 1-5) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell-surface proteins form complexes of both homo- and hetero-multimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1, and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin-binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Thrombospondin-2; Thrombospondin2; TSP2thrombospondin-2
基因别名: Thbs-2; Thbs2; TSP-2; TSP2
UniProt ID: (Mouse) Q03350
Entrez Gene ID: (Mouse) 21826, (Rat) 292406