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Invitrogen
Tiamulin Recombinant Mouse Monoclonal Antibody (2H8)
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Tiamulin Antibody (MA566279) in SDS-PAGE
SDS-PAGE characterization of Tiamulin under reducing conditions. Lane M: Protein marker (kDa); Lane TIA: Purified Tiamulin Recombinant Monoclonal (Product # MA566279). Tiamulin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-441.
产品信息
MA566279
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2H8
抗原
Conjugate of TIA hapten and KLH.
偶联物
形式
Liquid
浓度
7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Tiamulin is a semi-synthetic antibiotic belonging to the pleuromutilin class, extensively used in veterinary medicine to manage infections in swine and poultry caused by Gram-positive bacteria and mycoplasmas. Chemically, tiamulin features a tricyclic diterpene structure that includes a pleuromutilin core, contributing to its ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit. This mechanism effectively reduces bacterial growth by interrupting the assembly of essential proteins required for cellular functions. Tiamulin's pharmacokinetic profile includes high bioavailability and distribution across tissues, with oral administration common in feed or water. While its efficacy in controlling respiratory diseases in farm animals is well-documented, caution is advised concerning potential interactions with ionophore anticoccidials, which can lead to adverse effects. Research into tiamulin focuses on optimizing its therapeutic use while monitoring resistance development within target pathogens.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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