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Invitrogen
Tick-Borne Encephalitis Virus Envelope Recombinant Rabbit Monoclonal Antibody (HL4034)
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Tick-Borne Encephalitis Virus Envelope Antibody (MA568384) in ICC/IF
Immunocytochemistry analysis of Tick-Borne Encephalitis Virus Envelope in Mock and transfected 293T cells were fixed in 4% paraformaldehyde at RT for 15 min. Samples were incubated with Tick-Borne Encephalitis Virus Envelope recombinant monoclonal antibody (Product # MA568384) using a dilution of 1:500 (Green). Fluoroshield with DAPI (Blue).
产品信息
MA568384
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL4034
抗原
Recombinant fragment of Tick-borne encephalitis virus (TBEV) Envelope.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Tick-Borne Encephalitis Virus (TBEV) envelope protein, commonly referred to as protein E, is integral to the virus's structure and infectious capability. This glycoprotein is embedded in the viral lipid bilayer and is responsible for mediating attachment and entry into host cells. The E protein functions by binding to receptors on the surface of host cells, facilitating fusion between the viral and cellular membranes. Structurally, the envelope protein contains several domains: a stem-anchor region that is crucial for membrane fusion, and three domains (DI, DII, DIII) that are involved in receptor binding and immune evasion. Protein E is also a primary target for neutralizing antibodies, making it a key focus in vaccine development and serological diagnostics for TBEV. Research on the molecular biology of the E protein has led to advancements in understanding its role in pathogenesis and has driven efforts to develop subunit vaccines using virus-like particles (VLPs) that mimic the native envelope protein's structure, providing protective immunity against TBEV.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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