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Invitrogen
Tick-Borne Encephalitis Virus NS1 Recombinant Rabbit Monoclonal Antibody (HL3904)
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Tick-Borne Encephalitis Virus NS1 Antibody (MA568346) in ICC/IF
Immunocytochemistry analysis of Tick-Borne Encephalitis Virus NS1 in Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min. Samples were incubated with Tick-Borne Encephalitis Virus NS1 recombinant monoclonal antibody (Product # MA568346) using a dilution of 1:500 (Green). Fluoroshield with DAPI (Blue).
产品信息
MA568346
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL3904
抗原
Synthetic peptide of Tick-borne encephalitis virus (TBEV) NS1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Tick-Borne Encephalitis Virus (TBEV) non-structural protein 1 (NS1) is a glycoprotein that plays a pivotal role in the virus's replication and immune evasion. NS1 is expressed during acute TBEV infection and is secreted into the host's bloodstream. It is involved in modulating host immune responses, which can influence the severity of the infection. NS1-specific antibodies can be detected, serving as a marker for natural infections and aiding in the diagnosis of TBEV in vaccinated individuals. Eukaryotic expression systems are commonly employed to produce recombinant NS1, which is used in various immunological assays and research. The NS1 protein not only serves as a target for diagnostic purposes but also presents opportunities for developing therapeutic inhibitors. Research has shown that NS1 can affect dendritic cell effector functions, indicating its broader role in immune modulation. As TBEV causes severe neurological disease, understanding and targeting NS1 is crucial for improving diagnostic and therapeutic strategies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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