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Invitrogen
Tick-Borne Encephalitis Virus NS5 Recombinant Rabbit Monoclonal Antibody (HL3880)
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Tick-Borne Encephalitis Virus NS5 Antibody (MA566223) in ICC/IF
Immunocytochemistry analysis of Tick-Borne Encephalitis Virus NS5 in Mock and transfected 293T cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Tick-Borne Encephalitis Virus NS5 stained by Tick-Borne Encephalitis Virus NS5 Recombinant Monoclonal Antibody (Product # MA566223) diluted at 1:500. Blue: Fluoroshield with DAPI.
产品信息
MA566223
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL3880
抗原
Recombinant fragment of Tick-borne encephalitis virus NS5.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Tick-Borne Encephalitis Virus (TBEV) is a flavivirus transmitted by ticks, causing tick-borne encephalitis, a serious neurological disease. The nonstructural protein 5 (NS5) is the largest and most conserved protein of TBEV, playing a crucial role in viral replication and immune evasion. NS5 has two main functional domains: the RNA-dependent RNA polymerase (RdRp) and the methyltransferase (MTase). The RdRp domain is responsible for synthesizing viral RNA, while the MTase domain is involved in the capping of viral RNA, which is essential for RNA stability and efficient translation. Due to its vital functions in the viral life cycle, NS5 is a prime target for antiviral drug development. Understanding the structure and mechanisms of NS5 can lead to the creation of effective treatments and preventive measures against TBEV infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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