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Invitrogen
Tilmicosin Recombinant Mouse Monoclonal Antibody (3D1)
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Tilmicosin Antibody (MA566277) in SDS-PAGE
SDS-PAGE characterization of Tilmicosin under reducing conditions. Lane M: Protein marker (kDa); Lane TIM: Purified Tilmicosin Recombinant Monoclonal (Product # MA566277). Tilmicosin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-413.
产品信息
MA566277
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3D1
抗原
Conjugate of TIM hapten and KLH.
偶联物
形式
Liquid
浓度
1.8 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Tilmicosin is a 16-membered macrolide antibiotic synthesized semi-synthetically from a hydrolyzed derivative of tylosin, primarily used in veterinary medicine for livestock and poultry. It exhibits strong antibacterial activity, excellent pharmacokinetic properties, and immune-enhancing effects. Tilmicosin functions as a potent inhibitor of biofilm formation in Staphylococcus aureus and Staphylococcus epidermidis, even at sub-minimal inhibitory concentrations. Despite its broad-spectrum antibacterial efficacy, its clinical application is limited by low water solubility, resulting in incomplete absorption and low bioavailability. To address this, complexation with gamma-cyclodextrin has been explored to enhance its solubility and bioavailability. Additionally, tilmicosin has been studied for its drug-drug interaction potential, particularly with enrofloxacin, which affects its metabolism and residue profiles in vivo and in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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