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Invitrogen
Toralizumab Chimeric Recombinant Mouse Monoclonal Antibody (IDEC-131 (Toralizumab))
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产品信息
MA5-48309
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
IDEC-131 (Toralizumab)
抗原
The original monoclonal antibody was generated by immunization with a soluble fusion protein of human gp39 (gp39-CD8).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Specificity: This antibody is a non agonistic antibody specifc for human CD40 ligand.
靶标信息
Toralizumab works by binding to interferon gamma, which prevents it from interacting with its receptors on immune cells. This blocks the downstream signaling pathways that lead to inflammation and tissue damage in autoimmune diseases. By blocking interferon gamma, toralizumab aims to reduce inflammation and prevent further tissue damage in affected individuals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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