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A suggested positive control is human lung tissue lysate.
PA5-20742 can be used with blocking peptide PEP-0856.
Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Amyloidosis I; ATTR; carpal tunnel syndrome 1; epididymis luminal protein 111; pre-albumin; Prealbumin; prealbumin, amyloidosis type I; TBPA; thyroxine-binding prealbumin; Transthyretin
基因别名: AA408768; AI787086; CTS; CTS1; D17860; HEL111; HsT2651; Lr1; PALB; prealbumin; TBPA; Tt; TTR
UniProt ID: (Human) P02766, (Mouse) P07309, (Rat) P02767
Entrez Gene ID: (Human) 7276, (Mouse) 22139, (Rat) 24856