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Invitrogen
Triclosan Recombinant Mouse Monoclonal Antibody (3E6)
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Triclosan Antibody (MA566264) in SDS-PAGE
SDS-PAGE characterization of Triclosan under reducing conditions. Lane M: Protein marker (kDa); Lane TCS: Purified Triclosan Recombinant Monoclonal (Product # MA566264). Triclosan showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-641.
产品信息
MA566264
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3E6
抗原
Conjugate of TCS hapten and KLH.
偶联物
形式
Liquid
浓度
5.1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Triclosan, chemically known as 5-chloro-2-(2,4-dichlorophenoxy)phenol, is a broad-spectrum antibacterial agent that has been extensively used in various consumer products for over 30 years. It functions by inhibiting bacterial fatty acid synthesis, primarily targeting the enoyl-acyl carrier protein reductase enzyme, which is crucial for bacterial cell membrane production. Triclosan is lipophilic, allowing it to accumulate in human tissues and the environment, leading to concerns about its potential health risks and environmental impact. Studies have shown that triclosan exposure can lead to bacterial resistance, and its widespread use has resulted in its frequent detection in human biological samples and environmental residues. The molecular structure of triclosan includes a phenolic ring with chlorine substitutions, contributing to its antibacterial properties. Despite its effectiveness, the bioaccumulation and potential adverse effects have prompted regulatory scrutiny and a reevaluation of its safety in consumer products.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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