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Invitrogen
Trypsin Polyclonal Antibody
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Trypsin Antibody (PA5-106876) in ICC/IF
Immunofluorescent analysis of Trypsin in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Trypsin polyclonal antibody (Product # PA5-106876) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-106876
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PRSS1(Accession P07477), corresponding to amino acid residues V71-A121.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total PRSS1.
靶标信息
Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Anionic trypsin I; Anionic trypsin-1; Anionic trypsin-I; Beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; Pretrypsinogen I; Protease Serine 1; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; Serine protease 1; TCR V beta 4.1; TRYP8; trypsin 1; Trypsin I; Trypsin-1; trypsinogen; trypsinogen 1; trypsinogen 16; trypsinogen A
基因别名: PRSS1; PTRYI; RATPTRYI; TRP1; Try-1; TRY1; TRY4; Trygn16; TRYP1
UniProt ID: (Human) P07477, (Rat) P00762
Entrez Gene ID: (Human) 5644, (Rat) 24691, (Mouse) 114228
